Surveillance of the clinical use of mamushi (Gloydius blomhoffii) antivenom in tertiary care centers in Japan.

نویسندگان

  • Toru Hifumi
  • Akihiko Yamamoto
  • Kazunori Morokuma
  • Tomoko Ogasawara
  • Nobuaki Kiriu
  • Eiju Hasegawa
  • Junichi Inoue
  • Hiroshi Kato
  • Yuichi Koido
  • Motohide Takahashi
چکیده

We report the results of the first large-scale questionnaire surveillance on the clinical use of pit viper antivenom in tertiary care centers in Japan. The questionnaire surveillance was conducted over a period of 3 years (April 2006 to March 2009). Completed questionnaires were received from the tertiary care centers of 108 (49.3%) medical institutions. In that period, 574 cases of pit viper bites, including 2 severe cases, were reported. Antivenom was administered in 44% of the cases of pit viper bites, and of these cases, 2.4% had adverse reactions but no severe symptoms. Approximately half of the clinicians indicated that antivenom was effective. Antivenom was recognized to be safe; however, the remarkable finding was that although the severity of treated cases was unclear, some clinicians reported using cepharanthine as the first choice of treatment for pit viper bites.

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عنوان ژورنال:
  • Japanese journal of infectious diseases

دوره 64 5  شماره 

صفحات  -

تاریخ انتشار 2011